Software
Explore our open-source code repository, where we share computational tools and codes developed for our research projects. These resources are freely available to support transparency and collaboration within the scientific community. Don't hesitate to get in touch with me for inquiries and collaboration (farid.alisafaei@njit.edu)
Tension Anisotropy
Tension anisotropy drives fibroblast phenotypic transition by self-reinforcing cell–extracellular matrix mechanical feedback
F Alisafaei, D Shakiba, Y Hong, G Ramahdita, Y Huang, LE Iannucci, MD Davidson, M Jafari, J Qian, C Qu, D Ju, DR Flory, Y-Y Huang, P Gupta, S Jiang, A Mujahid, S Singamaneni, KM Pryse, P-HG Chao, JA Burdick, SP Lake, EL Elson, N Huebsch, VB Shenoy, GM Genin
Nature Materials, 2025
Code available at GitHub
Cellular Memory
Cell-matrix feedback controls stretch-induced cellular memory and fibroblast activation
Y Hong, X Peng, H Yu, M Jafari, D Shakiba, Y Huang, C Qu, EE Melika, AK Tawadros, A Mujahid, J Sandler, KM Pryse, JM Sacks, EL Elson, GM Genin, F Alisafaei
Proceedings of the National Academy of Sciences (PNAS), 2025
Code available at GitHub
Skin Grafting
Expansion limits of meshed split-thickness skin grafts
H Yu, M Jafari, A Mujahid, CF Garcia, J Shah, R Sinha, Y Huang, D Shakiba, Y Hong, D Cheraghali, J Pryce, JA Sandler, EL Elson, JM Sacks, G Genin, F Alisafaei
Acta Biomaterialia, 2025
Code available at GitHub
Vimentin Mechanobiology
Vimentin is a key regulator of cell mechanosensing through opposite actions on actomyosin and microtubule networks
F Alisafaei, K Mandal, R Saldanha, M Swoger, H Yang, X Shi, M Guo, H Hehnly, CA Castañeda, PA Janmey, AE Patteson, VB Shenoy
Communications Biology, 2024
Code available at GitHub