Mechanobiology of Microtubules

​Tension anisotropy drives phenotypic transitions of cells via two-way cell-ECM feedback

F Alisafaei, D Shakiba, LE Iannucci, MD Davidson, KM Pryse, PG Chao, JA Burdick, SP Lake, EL Elson, VB Shenoy, GM Genin

To Appear (Nature Materials), 2024

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Vimentin is a key regulator of cell mechanosensing through opposite actions on actomyosin and microtubule networks

F Alisafaei, K Mandal, R Saldanha, M Swoger, H Yang, X Shi, M Guo, H Hehnly, CA Castañeda, PA Janmey, AE Patteson, VB Shenoy

Communications Biology, 2024

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The balance between actomyosin contractility and microtubule polymerization regulates hierarchical protrusions that govern efficient fibroblast–collagen interactions

D Shakiba, F Alisafaei, A Savadipour, RA Rowe, Z Liu, KM Pryse, VB Shenoy, EL Elson, GM Genin

ACS Nano, 2020

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